Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300086 | 0.83 | CYP2C19 (0.51) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL2720302 | 0.82 | ABCB11 (0.60) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL10625243 | 0.81 | DRD1 (0.50) | OPRL1CYP2C19ABCB11DRD1ADRA2A | |
| SCHEMBL6376935 | 0.79 | ABCB11 (0.57) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL28404328 | 0.79 | ABCB11 (0.57) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL10620258 | 0.78 | MC4R (0.54) | OPRL1CYP2C19ABCB11DRD1ADRA2A | |
| SCHEMBL12723103 | 0.77 | DRD1 (0.44) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL10625272 | 0.77 | ADRA2A (0.46) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL11704970 | 0.76 | ADRA2A (0.46) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 | |
| SCHEMBL18845656 | 0.76 | ABCB11 (0.57) | CYP2C19ABCB11DRD1ADRA2ACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749692-A | COMBINATION OF SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4537894-A | ADMINISTERING SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1985-08-27 | — | — | US | disclosed |
| US-4464377-A | SYNERGISTIS BETA-ADRENERGIC BLOCKERS AND TICLOPIDINE | SANOFI-SYNTHELABO (FR) | 1984-08-07 | — | — | US | disclosed |