Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.65 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621413 | 0.89 | FDPS (0.71) | FDPSTBXAS1TERTPDE3A | |
| SCHEMBL1472092 | 0.79 | FDPS (1.00) | FDPSTBXAS1PDE3A | |
| SCHEMBL9460227 | 0.77 | FDPS (0.61) | FDPSTBXAS1GGPS1TERT | |
| SCHEMBL3431746 | 0.76 | TBXAS1 (0.66) | FDPSTBXAS1TERT | |
| Phosphoric Acid SCHEMBL5074163 | 0.75 | TBXAS1 (0.58) | FDPSTBXAS1TERT | |
| Phosphoric Acid SCHEMBL11769678 | 0.75 | TBXAS1 (0.58) | FDPSTBXAS1TERT | |
| SCHEMBL28062565 | 0.74 | TBXAS1 (0.69) | FDPSTBXAS1TERT | |
| SCHEMBL503743 | 0.74 | TBXAS1 (0.69) | FDPSTBXAS1TERT | |
| SCHEMBL9460152 | 0.73 | FDPS (0.65) | FDPSTBXAS1GGPS1 | |
| SCHEMBL5897424 | 0.72 | TBXAS1 (0.54) | FDPSTBXAS1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170228-B1 | DIPHOSPHONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1988-12-28 | — | — | EP | disclosed |
| US-4784993-A | Triazole containing diphosphonate compounds and the use thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1988-11-15 | — | — | US | disclosed |
| US-4687767-A | Certain 1-hydroxyethane, 1,1-di-phosphonic acid derivatives useful in treating calcium metabolism disturbances | BOEHRINGER MANNHEIM GMBH (DE) | 1987-08-18 | — | — | US | disclosed |
| EP-0170228-A1 | Diphosphonic-acid derivatives, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-02-05 | — | — | EP | disclosed |