Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626944 | 0.83 | NISCH (0.57) | KDM4ENISCH | |
| SCHEMBL10622396 | 0.80 | NISCH (0.43) | KDM4ENISCH | |
| SCHEMBL10625220 | 0.79 | NISCH (0.41) | KDM4ENISCH | |
| SCHEMBL548346 | 0.77 | NISCH (0.54) | NISCHPRMT1 | |
| Hydrochloric Acid SCHEMBL7050789 | 0.76 | LMNA (0.53) | LMNARECQLNISCHPRMT1 | |
| SCHEMBL6070119 | 0.72 | KDM4E (0.81) | KDM4ELMNA | |
| SCHEMBL11633801 | 0.72 | KDM4E (0.51) | KDM4E | |
| SCHEMBL11354774 | 0.72 | LMNA (0.56) | LMNARECQLNISCHPRMT1 | |
| SCHEMBL523059 | 0.69 | LMNA (0.96) | LMNARECQLNISCH | |
| SCHEMBL11661083 | 0.69 | KDM4E (0.66) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737514-A | Method for treating depression with thioxanthen-9-one derivatives | BURROUGHS WELLCOME CO. (US) | 1988-04-12 | — | — | US | disclosed |