Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | RECQL | P46063 | 1/20 | 0.96 |
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.66 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8188355 | 0.98 | LMNA (0.92) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL5476725 | 0.89 | NISCH (0.79) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL26126801 | 0.84 | NISCH (0.76) | LMNARECQLNISCH | |
| SCHEMBL8206164 | 0.83 | LMNA (0.68) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL26123421 | 0.83 | LMNA (0.68) | LMNARECQLNISCH | |
| SCHEMBL8202723 | 0.82 | NISCH (0.75) | LMNARECQLNISCH | |
| SCHEMBL8188588 | 0.81 | LMNA (0.63) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL8196146 | 0.79 | NISCH (0.88) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL1209074 | 0.79 | NISCH (0.66) | LMNARECQLNISCHTOP2ATOP2B | |
| SCHEMBL8141372 | 0.79 | NISCH (1.00) | LMNARECQLNISCHTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112715-A | Toner compositions containing a multi-purpose additive | EASTMAN KODAK COMPANY (US) | 1992-05-12 | — | — | US | claimed |
| US-5102765-A | Toner compositions containing 2-imidazolines, imidazoles or benzimidazoles as charge control agents | EASTMAN KODAK COMPANY (US) | 1992-04-07 | — | — | US | claimed |
| JP-4188119-A | — | — | None | — | — | JP | disclosed |
| EP-2421836-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | MSD K.K. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120029041-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | MSD K.K. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20110257196-A1 | COMPOUNDS FOR TREATMENT OF CANCER | ONCTERNAL THERAPEUTICS, INC | 2011-10-20 | — | — | US | disclosed |
| WO-2010123150-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-10-28 | — | — | WO | disclosed |
| EP-1287055-B9 | POWDER COMPOSITIONS FOR HEAT SENSITIVE SUBSTRATES | VALSPAR SOURCING INC (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-1287055-B1 | POWDER COMPOSITIONS FOR HEAT SENSITIVE SUBSTRATES | VALSPAR SOURCING INC (US) | 2010-01-06 | — | — | EP | disclosed |
| EP-1753727-A1 | NOVEL CIS-IMIDAZOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005110996-A1 | NOVEL CIS-IMIDAZOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-11-24 | — | — | WO | disclosed |
| EP-0331507-B1 | POLYVINYL CHLORIDE PLASTISOL COMPOSITION | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5154858-A | Mixture of 2-(p-chlorophenyl)imidazoline and a compound having an electron donative and an electron attractive group | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| JP-H04188119-A | NONLINEAR OPTICAL MATERIAL | MATSUSHITA ELECTRIC IND CO LTD | 1992-07-06 | — | — | JP | disclosed |
| EP-0487019-A2 | Use of a nonlinear optical compound | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5112715-A | Toner compositions containing a multi-purpose additive | EASTMAN KODAK COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5102765-A | Toner compositions containing 2-imidazolines, imidazoles or benzimidazoles as charge control agents | EASTMAN KODAK COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-4977201-A | Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings | ASAHI DENKA KOGYO K.K. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0331507-A1 | Polyvinyl chloride plastisol composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-3932450-A | Intermediates in the preparation of imidazo(2,1-alpha)isoindoles | SANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257196-A1 | COMPOUNDS FOR TREATMENT OF CANCER | KLK3, BRDT, ACP3 | LMNA 3427/4885RECQL 1894/4885NISCH 3272/4885 |
| US-20120029041-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | CLIC1, NAT1, NMRAL1 | LMNA 1996/4885RECQL 1868/4885NISCH 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.