Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148984 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30513721 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1202596 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3418071 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29527683 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11522777 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11277491 | 0.92 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10622164 | 0.91 | CYP19A1 (0.57) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11129891 | 0.90 | CYP19A1 (0.60) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13464403 | 0.88 | NQO1 (0.48) | NQO1CYP19A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782092-A | ANTITUMOR AGENTS, BACTERICIDES, FUNGICIDES | MID-AMERICA CANCER CENTER (US) | 1988-11-01 | — | — | US | disclosed |