Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619360 | 0.87 | TRPA1 (0.53) | DNTTPTGER2PPARGPTGER3PTGER4 | |
| SCHEMBL10619339 | 0.83 | TRPA1 (0.57) | DNTTPTGER2PPARGPTGER3PTGER4 | |
| SCHEMBL10621650 | 0.83 | TRPA1 (0.57) | DNTTPTGER2PPARGPTGER3PTGER4 | |
| SCHEMBL10619340 | 0.81 | DNTT (0.43) | DNTTPPARGTRPA1NR4A2PPARA | |
| SCHEMBL10704086 | 0.81 | DNTT (0.44) | DNTTPTGER2PPARGPTGER3PTGER4 | |
| SCHEMBL10619374 | 0.79 | TRPA1 (0.59) | PTGER2PPARGPTGER3PTGER4TRPA1 | |
| SCHEMBL10619366 | 0.79 | TRPA1 (0.59) | PTGER2PPARGPTGER3PTGER4TRPA1 | |
| SCHEMBL10621688 | 0.79 | DNTT (0.51) | DNTTPPARGTRPA1NR4A2PPARA | |
| SCHEMBL11866505 | 0.75 | TRPA1 (0.48) | DNTTPTGER2PPARGPTGER3PTGER4 | |
| SCHEMBL11866497 | 0.75 | TRPA1 (0.48) | DNTTPTGER2PPARGPTGER3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0106576-A2 | Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |