⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314773 | 0.75 | — | — | |
| SCHEMBL28732233 | 0.72 | — | — | |
| SCHEMBL9750725 | 0.72 | — | — | |
| SCHEMBL8132067 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL1314709 | 0.71 | — | — | |
| SCHEMBL11911968 | 0.69 | — | — | |
| SCHEMBL15003322 | 0.69 | — | — | |
| SCHEMBL108750 | 0.69 | — | — | |
| SCHEMBL12088873 | 0.69 | — | — | |
| SCHEMBL706722 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772692-A | AZETIDINONES | HOECHST UK LIMITED (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0069377-B1 | ANTIBACTERIAL PENEM DERIVATIVES | HOECHST UK LIMITED (GB) | 1988-06-22 | — | — | EP | disclosed |
| US-4585767-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |
| EP-0069377-A2 | Antibacterial penem derivatives | HOECHST UK LIMITED (GB) | 1983-01-12 | — | — | EP | disclosed |