Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 4/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017384 | 0.98 | CNR1 (0.58) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL10627901 | 0.97 | CNR1 (0.56) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL516208 | 0.82 | CNR2 (0.66) | CNR1ACHECNR2PTGER4KDM4E | |
| SCHEMBL9917435 | 0.80 | PDE5A (0.49) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL30602811 | 0.80 | PTGDR2 (0.46) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL17696321 | 0.79 | CNR1 (0.59) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL29342349 | 0.79 | CNR1 (0.59) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL928055 | 0.78 | SLC16A3 (0.58) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL29562418 | 0.78 | SLC16A3 (0.58) | CNR1ACHECNR2PDE5APTGER4 | |
| SCHEMBL9231345 | 0.77 | CNR1 (0.58) | CNR1ACHECNR2PDE5APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946786-A | A kind of preparation method of the indazole sodium salts of 1 benzyl, 3 hydroxyl 1H 3 | 白银澐新生物科技有限公司 | 2017-07-14 | — | — | CN | claimed |
| US-4749794-A | REMOVING 1-CHLORO-3-METHYLAMINOPROPANE IMPURITY FROM CRUDE PRODUCT | AZIENDE CHIMICHE RIUNUTE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1988-06-07 | — | — | US | claimed |
| CN-106946786-A | A kind of preparation method of the indazole sodium salts of 1 benzyl, 3 hydroxyl 1H 3 | 白银澐新生物科技有限公司 | 2017-07-14 | — | — | CN | disclosed |
| US-4749794-A | REMOVING 1-CHLORO-3-METHYLAMINOPROPANE IMPURITY FROM CRUDE PRODUCT | AZIENDE CHIMICHE RIUNUTE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1988-06-07 | — | — | US | disclosed |