Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602807 | 0.82 | PTGER4 (0.44) | PTGDR2NR1H2NR1H3PTGER4SRC | |
| SCHEMBL9917435 | 0.82 | PDE5A (0.49) | PTGDR2MAPTMEN1KMT2ACNR1 | |
| SCHEMBL1216862 | 0.82 | CYP1A2 (0.51) | PTGDR2GAAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3017384 | 0.81 | CNR1 (0.58) | MAPTCNR1ACHECNR2ALDH1A1 | |
| SCHEMBL10627901 | 0.80 | CNR1 (0.56) | MAPTCNR1ACHECNR2ALDH1A1 | |
| SCHEMBL10627892 | 0.80 | CNR1 (0.56) | MAPTCNR1ACHECNR2ALDH1A1 | |
| SCHEMBL30602797 | 0.79 | CNR2 (0.53) | PTGDR2MAPTMEN1KMT2AGALR3 | |
| SCHEMBL30695107 | 0.78 | CNR2 (0.53) | PTGDR2MAPTMEN1KMT2AGALR3 | |
| SCHEMBL17183855 | 0.78 | CNR2 (0.53) | PTGDR2MAPTMEN1KMT2AGALR3 | |
| SCHEMBL8441605 | 0.77 | PTGS2 (0.50) | MAPTKMT2ACNR1CNR2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |