Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628675 | 1.00 | SYK (0.55) | SYKKLK5KLK7TRPM8PPARA | |
| SCHEMBL11026023 | 0.91 | SYK (0.57) | SYKKLK5KLK7TRPM8PPARA | |
| SCHEMBL10628673 | 0.91 | SYK (0.57) | SYKKLK5KLK7TRPM8PPARA | |
| SCHEMBL10630534 | 0.89 | REN (0.54) | SYKKLK5RENCTSK | |
| SCHEMBL10634825 | 0.89 | REN (0.54) | SYKKLK5RENCTSK | |
| SCHEMBL10634879 | 0.89 | KLK5 (0.58) | SYKKLK5TRPM8RENCTSK | |
| SCHEMBL10630616 | 0.89 | KLK5 (0.58) | SYKKLK5TRPM8RENCTSK | |
| SCHEMBL27805991 | 0.86 | SYK (0.52) | SYKKLK5KLK7TRPM8PPARA | |
| SCHEMBL27805989 | 0.86 | SYK (0.52) | SYKKLK5KLK7TRPM8PPARA | |
| SCHEMBL16824022 | 0.83 | SYK (0.61) | SYKKLK5PPARACTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755592-A | Statine-containing peptides useful in medicaments | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |