Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19012408 | 0.80 | ALDH1A1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15224608 | 0.78 | PBRM1 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27004768 | 0.78 | NPC1 (0.53) | NPC1MAPTRAB9A | |
| SCHEMBL25873126 | 0.78 | ALDH1A1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21671652 | 0.77 | NPC1 (0.49) | GRIA4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15224808 | 0.77 | — | — | |
| SCHEMBL10794218 | 0.75 | TSHR (0.43) | GRIA4NPC1MAPTRAB9ATSHR | |
| SCHEMBL17042604 | 0.75 | ESR1 (0.52) | CYP3A4ALDH1A1 | |
| SCHEMBL9346982 | 0.75 | ESR1 (0.52) | CYP3A4ALDH1A1 | |
| SCHEMBL10716629 | 0.74 | MAPT (0.63) | NPC1MAPTRAB9ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754001-A | POLYESTERS, HIGH PERFORMANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | disclosed |
| EP-0162241-B1 | HEAT-CURABLE CYANATE RESIN AND ITS USE IN PREPARING COMPOSITES AND IPN'S | BAYER AG (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4631319-A | WITH A POLYESTER, INTERPENETRATING POLYMER NETWORKS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |
| EP-0162241-A1 | Heat-curable cyanate resin and its use in preparing composites and IPN's | BAYER AG (DE) | 1985-11-27 | — | — | EP | disclosed |