Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.83 |
| ▸ | PGR | P06401 | 3/20 | 0.83 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.64 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630170 | 1.00 | NR1I2 (0.83) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10632097 | 0.94 | NR1I2 (0.81) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10632115 | 0.94 | NR1I2 (0.81) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9076396 | 0.92 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004971 | 0.92 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004976 | 0.92 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9076389 | 0.92 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL4707015 | 0.92 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL192780 | 0.92 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL27487467 | 0.92 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288435-A | 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-08 | — | — | US | claimed |
| US-4782158-A | CEPHEM ANTIBIOTIC INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4599426-A | INTERMEDIATES FOR CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO. (JP) | 1986-07-08 | — | — | US | disclosed |
| US-4506076-A | MICROBIOCIDES, CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-19 | — | — | US | disclosed |
| EP-0009548-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-16 | — | — | EP | disclosed |
| EP-0059486-A1 | New starting compounds for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-08 | — | — | EP | disclosed |
| US-4288435-A | 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-08 | — | — | US | disclosed |
| EP-0009548-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |