Diphenylether

Diphenylether

SCHEMBL10632533

C(#CCOc1ccccc1)COc1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 10/20 0.57
TSHR P16473 1/20 0.57
PLA2G2A P14555 1/20 0.52
KCNH2 Q12809 1/20 0.52
KCNA3 P22001 1/20 0.48
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
MAOA P21397 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9808291 0.93 KCNH2 (0.57) LTA4HTSHRKCNH2KCNA3CA12
SCHEMBL10833567 0.86 CA12 (0.61) LTA4HTSHRPLA2G2AKCNH2CA12
SCHEMBL11573954 0.86 LTA4H (0.52) LTA4HTSHRPLA2G2AKCNH2NR1H2
SCHEMBL10571938 0.84 KCNH2 (0.50) LTA4HKCNH2KCNA3CA12CA1
SCHEMBL1790840 0.83 KCNH2 (0.53) LTA4HTSHRKCNH2KCNA3CA12
SCHEMBL14085300 0.82 KCNH2 (0.53) LTA4HKCNH2KCNA3CA12CA1
SCHEMBL7501197 0.82 KCNH2 (0.49) LTA4HKCNH2KCNA3CA12CA1
SCHEMBL4521402 0.82 KCNH2 (0.49) LTA4HKCNH2KCNA3CA12CA1
SCHEMBL5658625 0.82 ALDH1A1 (0.50) LTA4HKCNH2KCNA3CA12CA1
SCHEMBL3982634 0.82 TAAR1 (0.50) LTA4HPLA2G2AKCNH2KCNA3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754097-A USING CATALYST COMPLEX CONTAINING GROUP SIX COMPOUND AND GROUP THREE OR FOUR METAL ALKOXIDE OR PHENOXIDE ETHYL CORPORATION (US) 1988-06-28 US disclosed
US-4704377-A BIMETALLIC COMPLEX CATALYSTS ETHYL CORPORATION (US) 1987-11-03 US disclosed