Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637871 | 0.95 | HSD17B3 (0.62) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL2026598 | 0.87 | HSD17B3 (0.60) | HSD17B3ALDH1A1MAPTCTNNB1 | |
| SCHEMBL13085731 | 0.87 | HSD17B3 (0.62) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL3943135 | 0.84 | HDAC1 (0.65) | ALDH1A1MAPTCTNNB1 | |
| SCHEMBL10482996 | 0.83 | HSD17B3 (0.60) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL7392363 | 0.83 | L3MBTL1 (0.53) | HSD17B3ALDH1A1MAPTCTNNB1 | |
| Phenol SCHEMBL28277487 | 0.83 | HSD17B3 (0.77) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL28310663 | 0.82 | CTNNB1 (0.53) | ALDH1A1MAPTESR1ESR2CTNNB1 | |
| SCHEMBL30817861 | 0.82 | CTNNB1 (0.47) | HSD17B3ALDH1A1MAPTCTNNB1 | |
| SCHEMBL17952793 | 0.81 | HSD17B3 (0.56) | HSD17B3HTTMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181568-A2 | Anti-inflammatory/anti-allergic compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1986-05-21 | — | — | EP | claimed |
| US-4794188-A | LIPOXYGENASE INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0234500-A1 | Antiasthma inhalation compositions | RORER PHARMACEUTICAL CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| US-4567184-A | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies | USV PHARMACEUTICAL CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |