Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632540 | 0.95 | HSD17B3 (0.64) | HSD17B3CTNNB1HTTALDH1A1MEN1 | |
| SCHEMBL2026598 | 0.89 | HSD17B3 (0.60) | HSD17B3CTNNB1CA12CA1CA2 | |
| SCHEMBL10482996 | 0.89 | HSD17B3 (0.60) | HSD17B3HTR7HTTALDH1A1MEN1 | |
| SCHEMBL28310663 | 0.84 | CTNNB1 (0.53) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL3896481 | 0.82 | OGG1 (0.58) | HSD17B3HTR7ALDH1A1MEN1MAPT | |
| SCHEMBL4931177 | 0.82 | CTNNB1 (0.56) | HSD17B3HTR7CTNNB1ALDH1A1MAPT | |
| SCHEMBL6259203 | 0.82 | CTNNB1 (0.55) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL3943135 | 0.82 | HDAC1 (0.65) | CTNNB1CA12CA1CA2CA6 | |
| SCHEMBL29315332 | 0.82 | HSD17B3 (0.53) | HSD17B3HTR7ALDH1A1MAPT | |
| SCHEMBL27547875 | 0.82 | HSD17B3 (0.53) | HSD17B3HTR7MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061756-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-11-14 | — | — | EP | disclosed |
| US-9914695-B2 | Two-step process for preparing 3-substituted phenylalkylamines | MALLINCKRODT LLC (US) | 2018-03-13 | — | — | US | disclosed |
| US-9635857-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9635857-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9635857-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-3061756-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-18 | — | — | US | disclosed |
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-18 | — | — | US | disclosed |
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-18 | — | — | US | disclosed |
| WO-2015060461-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 | 2015-04-30 | — | — | WO | disclosed |
| CN-103119049-A | Organic phosphorus compound and method for producing same | UBE INDUSTRIES | 2013-05-22 | — | — | CN | disclosed |
| CN-101437395-A | Chemical compounds | SMITHKLINE BEECHAM CORP (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101370380-A | Chemical compounds | SMITHKLINE BEECHAM CORP (US) | 2009-02-18 | — | — | CN | disclosed |
| US-20080306036-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Modulators | SMITHKLINE BEECHAM CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
| EP-1951216-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1951041-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062190-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007062145-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306036-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Modulators | ESR2, GPER1, ESR1 | HSD17B3 98/4885HTR7 741/4885CTNNB1 3315/4885 |
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | HSD17B3 99/4885HTR7 595/4885CTNNB1 3727/4885 |
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | MRPS17, TAOK1, TAOK3 | HSD17B3 670/4885HTR7 2072/4885CTNNB1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.