Dimethylformamide

Dimethylformamide

SCHEMBL10632579

CC(=O)N(C)C.CN(C)C=O.O=CN(c1ccccc1)c1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RECQL P46063 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTT P42858 2/20 0.36
GLA P06280 1/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007098 0.81 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1TSHRL3MBTL1
SCHEMBL43388 0.79 ALDH1A1 (0.42) KMT2AMEN1ALDH1A1TSHRL3MBTL1
SCHEMBL5516786 0.79 ALDH1A1 (0.42) KMT2AMEN1ALDH1A1TSHRL3MBTL1
Dimethylformamide SCHEMBL57861 0.74 TSHR (0.60) ALDH1A1TSHR
Dimethylformamide SCHEMBL28741372 0.74 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1TSHRL3MBTL1
Dimethylformamide SCHEMBL15328002 0.73 RELA (0.52) KMT2AMEN1ALDH1A1TSHRL3MBTL1
Dimethylformamide SCHEMBL28235494 0.73 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1TSHRL3MBTL1
SCHEMBL172583 0.72 CA12 (0.44) KMT2AMEN1ALDH1A1TSHRCYP2C19
Toluene SCHEMBL11506228 0.72 TSHR (0.48) KMT2AMEN1ALDH1A1TSHRRECQL
SCHEMBL3248552 0.72 ALDH1A1 (0.43) KMT2AMEN1ALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4751272-A POLYMERIZING TRIOXANE AND CYCLIC ETHER; BORON TRIFLUORIDE CATALYST TORAY INDUSTRIES, INC. (JP) 1988-06-14 US disclosed
EP-0244245-A2 Process for producing oxymethylene copolymer and resinous composition TORAY INDUSTRIES, INC. (JP) 1987-11-04 EP disclosed