SCHEMBL10633429

SCHEMBL10633429

COC(=O)[C@@H](N)CCC(N)=O.N=C=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
KMT2A Q03164 1/20 0.47
DPP4 P27487 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
LTA4H P09960 3/20 0.38
FOLH1 Q04609 1/20 0.36
SLC1A1 P43005 2/20 0.33
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GSR P00390 1/20 0.31
CYP1A2 P05177 1/20 0.31
GRIK1 P39086 1/20 0.31
GRM5 P41594 1/20 0.31
GRIA1 P42261 1/20 0.31
GRIA2 P42262 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10192702 0.91 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL716803 0.91 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL321431 0.91 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2082961 0.91 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
Hydrochloric Acid SCHEMBL595131 0.89 ALOX15 (0.54) ALOX15BLMPMP22KMT2ADPP4
Hydrochloric Acid SCHEMBL2083204 0.89 ALOX15 (0.54) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL21268583 0.86 SLC1A1 (0.48) BLMDPP4DPP8DPP9LTA4H
SCHEMBL20474981 0.86 SLC1A1 (0.47) ALOX15BLMPMP22KMT2ALTA4H
SCHEMBL10633361 0.86 SLC1A1 (0.47) ALOX15BLMPMP22KMT2ALTA4H
SCHEMBL10402326 0.81 CA1 (0.40) DPP4DPP8DPP9LTA4HSLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4740611-A N,N'-disubstituted ureas THE STANDARD OIL COMPANY (US) 1988-04-26 US disclosed
US-4705864-A Aryl oxime derivatives of hydantoins THE STANDARD OIL COMPANY (US) 1987-11-10 US disclosed