SCHEMBL716803

SCHEMBL716803

COC(=O)C(N)CCC(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
DPP4 P27487 2/20 0.49
DPP8 Q6V1X1 2/20 0.49
DPP9 Q86TI2 2/20 0.49
LTA4H P09960 3/20 0.42
FOLH1 Q04609 1/20 0.41
SLC1A1 P43005 2/20 0.38
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321431 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL10192702 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2082961 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
Hydrochloric Acid SCHEMBL595131 0.98 ALOX15 (0.54) ALOX15BLMPMP22KMT2ADPP4
Hydrochloric Acid SCHEMBL2083204 0.98 ALOX15 (0.54) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL10633429 0.91 ALOX15 (0.47) ALOX15BLMPMP22KMT2ADPP4
Glutamic Acid SCHEMBL19128265 0.88 ALOX15 (0.63) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL11776470 0.84 SMN1; SMN2 (0.42) LTA4HSLC1A1CA1CA2SMN1; SMN2
SCHEMBL12601005 0.83 LTA4H (0.40) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL18870212 0.83 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110407807-A A kind of preparation method of lenalidomide GANSU TAISHENG CHEMICAL TECH CO LTD 2019-11-05 CN claimed
CN-105399751-A BUPRENORPHINE ANALOGS PURDUE PHARMA LP 2016-03-16 CN claimed
CN-103154000-A Buprenorphine analogs PURDUE PHARMA LP 2013-06-12 CN claimed
CN-101591375-B Compound with analgesic activity, preparation method and application thereof UNIV CAPITAL MEDICAL 2011-11-09 CN claimed
CN-101190895-B N-[(3S)-1,2,3,4-tetrahydroisoquinolino-3-formacyl]amino acid, preparation method and application thereof CAPITAL UNIVERSITY OF MEDICAL SCIENCES 2010-05-26 CN claimed
CN-101665484-A Method for preparing lenalidomide SHANGHAI HAOYUAN CHEMEXPRESS B 2010-03-10 CN claimed
CN-101591375-A Has compound of analgesic activities and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-02 CN claimed
EP-4734770-A1 COMPOUNDS THAT MODULATE GPRC6A RECEPTOR AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2026-05-06 EP disclosed
EP-4673146-A2 METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS Biohaven Therapeutics Ltd. (VG) 2026-01-07 EP disclosed
CN-120040435-A Mangiferin and derivatives thereof, preparation method and medical application thereof 安徽中医药大学 2025-05-27 CN disclosed
WO-2025006362-A1 COMPOUNDS THAT MODULATE GPRC6A RECEPTOR AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-01-02 WO disclosed
WO-2024182465-A2 METHODS FOR TREATING OBSESSIVE COMPULSIVE RELATED DISORDERS, TIC DISORDERS AND GLUTAMATE EXCITOTOXICITY RELATED DISORDERS ALCO THERAPEUTICS, LLC (US) 2024-09-06 WO disclosed
CN-116199643-A Phenothiazine compound containing isopropanol substructure, and preparation and application thereof 贵州大学 2023-06-02 CN disclosed
WO-1996000391-A1 METHODS FOR THE SYNTHESIS OF DIKETOPIPERAZINES AFFYMAX TECHNOLOGIES N.V. (AN) 1996-01-04 WO disclosed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN disclosed
CN-1079473-A The N-phosphinylidyne small peptide UNIV QINGHUA (CN) 1993-12-15 CN disclosed
EP-0485517-A1 SYNTHESIS OF GLYCOSIDES HAVING PREDETERMINED STEREOCHEMISTRY YALE UNIVERSITY (US) 1992-05-20 EP disclosed
WO-1991002739-A1 SYNTHESIS OF GLYCOSIDES HAVING PREDETERMINED STEREOCHEMISTRY YALE UNIVERSITY (US) 1991-03-07 WO disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 US disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP disclosed