Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 20/20 | 0.65 |
| ▸ | BCHE | P06276 | 16/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631817 | 0.81 | ACHE (0.61) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10486940 | 0.81 | ACHE (0.67) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9173696 | 0.79 | ACHE (0.61) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29817682 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9172823 | 0.78 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29817805 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9175875 | 0.77 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL29817798 | 0.77 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10351438 | 0.76 | ACHE (0.64) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9173459 | 0.76 | ACHE (0.53) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762841-A | Substituted 9-amino-spiro(cycloalkyl(b)quinoline-2,1'cycloalkanes) | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-08-09 | — | — | US | claimed |