Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | EBP | Q15125 | 8/20 | 0.36 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10634915 | 0.88 | ACLY (0.35) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10634936 | 0.88 | EBP (0.38) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10634885 | 0.87 | ACLY (0.36) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10349851 | 0.87 | ACLY (0.35) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10634974 | 0.86 | ACLY (0.34) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10349522 | 0.84 | ACLY (0.35) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10638570 | 0.82 | EBP (0.40) | ACLYACACAEBPHSD11B1CDC25B | |
| Ferulate SCHEMBL2563897 | 0.80 | MEN1 (0.42) | ACLYACACAEBPHSD11B1PTGS1 | |
| SCHEMBL10638415 | 0.79 | EBP (0.40) | ACLYACACAEBPCDC25AHSD11B1 | |
| SCHEMBL10638617 | 0.78 | EBP (0.41) | ACLYACACAEBPHSD11B1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |