Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159792 | 0.82 | EBP (0.47) | ACLYACACAEBPHSD11B1 | |
| SCHEMBL12152370 | 0.80 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL10634915 | 0.80 | ACLY (0.35) | ACLYACACAEBPHSD11B1 | |
| SCHEMBL10635509 | 0.80 | ACLY (0.36) | ACLYACACAEBPPTGS1HSD11B1 | |
| SCHEMBL10634885 | 0.78 | ACLY (0.36) | ACLYACACAEBPPTGS1HSD11B1 | |
| SCHEMBL10349522 | 0.76 | ACLY (0.35) | ACLYACACAEBPPTGS1HSD11B1 | |
| Niacin SCHEMBL6684757 | 0.76 | EBP (0.39) | GAAACLYACACAAPPEBP | |
| SCHEMBL6341662 | 0.75 | HSD11B1 (0.45) | ACLYACACAEBPTOP2APTGS1 | |
| SCHEMBL10635626 | 0.75 | EBP (0.39) | ACLYACACAEBPHSD11B1 | |
| SCHEMBL10638477 | 0.75 | EBP (0.39) | ACLYACACAEBPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011702-B1 | STABILIZED RICE BRAN DERIVATIVES FOR TREATING DIABETES | RICEX COMPANY INC (US) | 2011-11-02 | — | — | EP | disclosed |
| US-6733799-B2 | STABILIZED RICE BRAN DERIVATIVE, SOLUBILIZED, INSOLUBILIZED, AND/OR ENZYME TREATED; INHIBITING PLATELET AGGREGATION; REDUCING SERUM TOTAL CHOLESTEROL, LOW DENSITY LIPOPROTEIN (LDL) CHOLESTEROL, APOLIPOPROTEIN B AND TRIGLYCERIDE LEVELS | THE RICEX COMPANY | 2004-05-11 | — | — | US | disclosed |
| EP-1011702-A4 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | RICEX COMPANY (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6558714-B2 | Ingesting stabilized rice bran derivative selected from enzyme treated stabilized rice bran, an insolubilized fraction and mixture to reduce serum total cholesterol, LDL cholesterol, apolipoprotein B and triglyceride levels | THE RICEX COMPANY | 2003-05-06 | — | — | US | disclosed |
| US-6350473-B1 | INGESTING THERAPEUTICALLY EFFECTIVE AMOUNT OF STABILIZED RICE BRAN DERIVATIVE TO REDUCE SERUM GLUCOSE IN MAMMAL | THE RICE COMPANY | 2002-02-26 | — | — | US | disclosed |
| US-6303586-B1 | INGESTING THERAPEUTICALLY EFFECTIVE AMOUNT OF STABILIZED RICE BRAN SOLUBILIZED FRACTION, WHEREIN SAID STABILIZED RICE BRAN SOLUBILIZED FRACTION IS FREE OF STABILIZED RICE BRAN INSOLUBILIZED FRACTION TO REDUCING SERUM GLUCOSE IN MAMMAL | THE RICEX COMPANY | 2001-10-16 | — | — | US | disclosed |
| US-6126943-A | BY INGESTING A STABILIZED RICE BRAN DERIVATIVE. | THE RICEX COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| EP-1011702-A1 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | The Ricex Company (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999011144-A1 | A METHOD FOR TREATING HYPERCHOLESTEROLEMIA, HYPERLIPIDEMIA, AND ATHEROSCLEROSIS | THE RICEX COMPANY, INC. (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1999010002-A1 | A METHOD FOR TREATING DIABETES, HYPERGLYCEMIA AND HYPOGLYCEMIA | THE RICEX COMPANY, INC. (US) | 1999-03-04 | — | — | WO | disclosed |