⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914912 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL27897570 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL3325908 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL11298285 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL28801700 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL381494 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL3326811 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL1664514 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL3092823 | 0.98 | OPRM1 (0.48) | — | |
| SCHEMBL9828480 | 0.98 | OPRM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4681737-B2 | — | — | 2011-05-11 | — | — | JP | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| EP-1678164-B1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORP (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1678146-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1678164-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1667700-A2 | CYCLIC PEPTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF SEXUAL DYSFUNCTION | Palatin Technologies, Inc. (US) | 2006-06-14 | — | — | EP | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| US-20050164914-A1 | Metallopeptide compositions for treatment of sexual dysfunction | PALATIN TECHNOLOGIES, INC. (US) | 2005-07-28 | — | — | US | claimed |
| WO-2005040133-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2005035527-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-21 | — | — | WO | claimed |
| WO-2005014617-A2 | CYCLIC PEPTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF SEXUAL DYSFUNCTION | PALATIN TECHNOLOGIES, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| US-6777408-B1 | AFFINITY AND SELECTIVITY FOR SOMATOSTATIN RECEPTORS; SUCH AS 5-(2-CHLOROPHENYL)-1,3,6,7,8,9-HEXAHYDRO-1-(2-PHENYLETHYL)-2H -PYRIDO(4',3':4,5)THIENO(2,3-E)-1,4-DIAZEPINE-2-ONE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-08-17 | — | — | US | claimed |
| US-20040138136-A1 | Cyclic peptide compositions and methods for treatment of sexual dysfunction | PALATIN TECHNOLOGIES, INC. | 2004-07-15 | — | — | US | claimed |
| WO-2004005324-A2 | PEPTIDE COMPOSITION FOR TREATMENT OF SEXUAL DYSFUNCTION | PALATIN TECHNOLOGIES, INC. (US) | 2004-01-15 | — | — | WO | claimed |
| EP-1171444-B1 | PYRIDO-THIENO-DIAZEPINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID PYRIDO-THIENO-DIAZEPINES | SOD CONSEILS RECH APPLIC (FR) | 2003-07-02 | — | — | EP | claimed |
| EP-1171444-A1 | PYRIDO-THIENO-DIAZEPINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID PYRIDO-THIENO-DIAZEPINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-01-16 | — | — | EP | claimed |
| WO-2000061587-A1 | PYRIDO-THIENO-DIAZEPINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID PYRIDO-THIENO-DIAZEPINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2024086381-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | ENDEVICA BIO, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |