Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914912 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL9828480 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL27897570 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL28801700 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL11298285 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL3092823 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL381494 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL1664514 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL3326811 | 1.00 | OPRM1 (0.48) | OPRM1LAP3SPHK1MAPTTP53 | |
| SCHEMBL1063647 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071358-A1 | BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON | VERTA RESEARCH-PRODUCTION COMPANY" LTD (RU) | 2020-03-05 | — | — | US | claimed |
| CN-106164087-A | Antimicrobial polypeptide and application thereof | 莱顿大学学术医院以LUMC 的名义运作 | 2016-11-23 | — | — | CN | claimed |
| CN-105555290-A | Antimicrobial peptide | ACADEMISCH ZIEKENHUIS LEIDEN | 2016-05-04 | — | — | CN | claimed |
| US-4299821-A | HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-11-10 | — | — | US | claimed |
| US-4172130-A | α-AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1979-10-23 | — | — | US | claimed |
| CN-112300250-B | Anidulafungin analogue and preparation method thereof | 上海医药工业研究院 | 2024-03-19 | — | — | CN | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210205463-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2021-07-08 | — | — | US | disclosed |
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| EP-3185908-B1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20200071358-A1 | BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON | VERTA RESEARCH-PRODUCTION COMPANY" LTD (RU) | 2020-03-05 | — | — | US | disclosed |
| WO-2018143840-A1 | BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON | Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" | 2018-08-09 | — | — | WO | disclosed |
| US-4309342-A | SYNERGISTIC EFFECT WITH ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1982-01-05 | — | — | US | disclosed |
| US-4299821-A | HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-11-10 | — | — | US | disclosed |
| US-4299821-A | HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-11-10 | — | — | US | disclosed |
| US-4201854-A | N,N-DIMETHYLALKYLENEDIAMINE DERIVATIVE CURING AGENT | CIBA-GEIGY CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |
| US-4183909-A | DIAGNOSTIC TOOL FOR GASTROINTESTINAL DISORDERS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-01-15 | — | — | US | disclosed |
| US-4183909-A | DIAGNOSTIC TOOL FOR GASTROINTESTINAL DISORDERS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-01-15 | — | — | US | disclosed |
| US-4172130-A | α-AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1979-10-23 | — | — | US | disclosed |
| US-4172130-A | α-AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1979-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10967068-B2 | Stability-modulating linkers for use with antibody drug conjugates | FCGR2A, FCGRT, FCGR1A | OPRM1 3349/4885LAP3 1449/4885SPHK1 2797/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | OPRM1 2686/4885LAP3 60/4885SPHK1 1189/4885 |
| US-20210205463-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | FCGR2A, FCGRT, FCGR1A | OPRM1 3349/4885LAP3 1449/4885SPHK1 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.