Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626 | 0.88 | HRH3 (0.63) | HRH3KCNH2HRH1 | |
| SCHEMBL12050749 | 0.87 | HRH3 (1.00) | HRH3KCNH2HRH1 | |
| SCHEMBL10377 | 0.83 | NPC1 (0.58) | HRH3HRH1 | |
| SCHEMBL3782542 | 0.83 | HRH3 (0.68) | HRH3HRH1 | |
| SCHEMBL2824059 | 0.82 | HRH3 (0.67) | HRH3 | |
| SCHEMBL4094339 | 0.81 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL12050645 | 0.81 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL492219 | 0.81 | HRH3 (0.75) | HRH3 | |
| SCHEMBL2824056 | 0.81 | HRH3 (0.66) | HRH3 | |
| SCHEMBL2821540 | 0.80 | HRH3 (0.86) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |