Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10634636 | 0.97 | THRA (0.44) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10634779 | 0.97 | THRA (0.41) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10638116 | 0.94 | THRA (0.38) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10638326 | 0.94 | THRA (0.44) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10821991 | 0.94 | THRA (0.49) | THRATHRBSPHK1SPHK2HSD17B10 | |
| SCHEMBL10637394 | 0.93 | THRA (0.46) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10640523 | 0.93 | RARB (0.41) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10640002 | 0.90 | THRA (0.36) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10634624 | 0.90 | RARB (0.41) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL9189563 | 0.89 | SPHK1 (0.44) | THRATHRBSPHK1SPHK2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087679-B1 | 1,3-DIOXANES | MERCK PATENT GmbH (DE) | 1988-06-22 | — | — | EP | disclosed |