Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.36 |
| ▸ | RARB | P10826 | 5/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638116 | 0.96 | THRA (0.38) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL10640523 | 0.94 | RARB (0.41) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL10634636 | 0.93 | THRA (0.44) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL10640463 | 0.91 | NISCH (0.35) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10634779 | 0.90 | THRA (0.41) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL10637166 | 0.90 | THRA (0.44) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL10634624 | 0.89 | RARB (0.41) | THRATHRBSPHK1SPHK2RARB | |
| SCHEMBL7781473 | 0.88 | THRA (0.34) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL7781478 | 0.88 | THRA (0.34) | THRATHRBSPHK1SPHK2HRH3 | |
| SCHEMBL10638326 | 0.87 | THRA (0.44) | THRATHRBSPHK1SPHK2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087679-B1 | 1,3-DIOXANES | MERCK PATENT GmbH (DE) | 1988-06-22 | — | — | EP | disclosed |
| EP-0087679-A2 | 1,3-Dioxanes | MERCK PATENT GmbH (DE) | 1983-09-07 | — | — | EP | disclosed |