SCHEMBL1063804

SCHEMBL1063804

C[SiH](C)N(C(=O)C(F)(F)F)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20312955 0.74 CHRM2 (0.31)
SCHEMBL3618071 0.72 CHRM2 (0.31)
SCHEMBL3643142 0.70 CHRM2 (0.33)
SCHEMBL16709296 0.68
SCHEMBL5620718 0.68 CHRM2 (0.30)
SCHEMBL24256512 0.67 CHRM2 (0.34)
SCHEMBL444539 0.67
SCHEMBL6675892 0.67 CHRM2 (0.35)
SCHEMBL14967109 0.67
SCHEMBL2351398 0.65 CHRM2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3287592-A None JP disclosed
EP-2861726-B1 RECOMBINANT MICROORGANISM FOR THE FERMENTATIVE PRODUCTION OF METHIONINE EVONIK DEGUSSA GMBH (DE) 2017-05-31 EP disclosed
US-9506093-B2 Recombinant microorganism for the fermentative production of methionine METABOLIC EXPLORER (FR) 2016-11-29 US disclosed
US-20160145649-A1 Ethanol Production in Microorganisms JOULE UNLTD TECHNOLOGIES INC (US) 2016-05-26 US disclosed
EP-2998402-A1 ETHANOL PRODUCTION BY MICROORGANISMS Joule Unlimited Technologies, Inc. (US) 2016-03-23 EP disclosed
US-9284579-B2 Ethanol production in microorganisms JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2016-03-15 US disclosed
US-20160040191-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST JOULE BIOTECHNOLOGIES 2016-02-11 US disclosed
US-20150368675-A1 Ethanol Production in Microorganisms ARES CAPITAL CORPORATION 2015-12-24 US disclosed
US-9163264-B2 Ethanol production in microorganisms JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2015-10-20 US disclosed
US-20150247175-A1 Recombinant Microorganism for the Fermentative Production of Methionine EVONIK OPERATIONS GMBH (DE) 2015-09-03 US disclosed
WO-2009115497-A1 POLYPEPTIDE HAVING GLYOXALASE III ACTIVITY, POLYNUCLEOTIDE ENCODING THE SAME AND USES THEREOF METABOLIC EXPLORER (FR) 2009-09-24 WO disclosed
WO-2009111513-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST JOULE BIOTECHNOLOGIES, INC. (US) 2009-09-11 WO disclosed
EP-2030975-A1 CEFDINIR synthesis process ACS DOBFAR S.p.A. (IT) 2009-03-04 EP disclosed
US-20090029424-A1 Recombinant enzyme with altered feedback sensitivity METABOLIC EXPLORER (FR) 2009-01-29 US disclosed
US-20080286840-A1 Microorganisms Comprising Enzymes Express with Low Gamma-Elimination Activity METABOLIC EXPLORER (FR) 2008-11-20 US disclosed
EP-1846547-A2 MICROORGANISMS COMPRISING ENZYMES EXPRESSED WITH LOW GAMMA-ELIMINATION ACTIVITY Metabolic Explorer (FR) 2007-10-24 EP disclosed
WO-2006082254-A2 MICROORGANISMS COMPRISING ENZYMES EXPRESSED WITH LOW GAMMA-ELIMINATION ACTIVITY METABOLIC EXPLORER (FR) 2006-08-10 WO disclosed
US-5800979-A Gas chromatography/mass spectrometric determination of folic acid coenzymes KOLHOUSE J FRED (US) 1998-09-01 US disclosed
US-5212096-A Purification and quantitative analysis UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1993-05-18 US disclosed
JP-H03287592-A PRODUCTION OF N,O-BIS(T-BUTYLDIMETHYLSILYL)-TRIFLUOROACETAMIDE SHIN ETSU CHEM CO LTD 1991-12-18 JP disclosed