SCHEMBL6675892

SCHEMBL6675892

CCN(C(=O)C(F)(F)F)[SiH](C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.35
CHRM4 P08173 3/20 0.35
CHRM5 P08912 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM3 P20309 3/20 0.35
MLYCD O95822 1/20 0.33
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5136628 0.79 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5620718 0.77 CHRM2 (0.30) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4439111 0.77 FAAH (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2354299 0.76 MLYCD (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15218741 0.75 CHRM2 (0.42) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6228284 0.72
SCHEMBL249531 0.72 MLYCD (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3618071 0.72 CHRM2 (0.31) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3643142 0.70 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9321696 0.68 CHRM2 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266903-B1 Method of preparing an organosilicon compound DOW CORNING ASIA LTD (JP) 2004-09-29 EP disclosed
EP-1266903-A1 Method of preparing an organosilicon compound DOW CORNING ASIA, Ltd. (JP) 2002-12-18 EP disclosed
US-6326506-B1 HYDROSILATION DOW CORNING ASIA, LTD. (JP) 2001-12-04 US disclosed