Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.61 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.52 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | SPR | P35270 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633932 | 0.83 | GUSB (0.49) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10637521 | 0.83 | TNKS2 (0.52) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10640119 | 0.83 | NPC1 (0.52) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10634743 | 0.82 | HTR3A (0.56) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10640495 | 0.82 | EGLN1 (0.51) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10638059 | 0.82 | EGLN1 (0.51) | MGLLHTR3AEGLN1KMT2ACASP3 | |
| SCHEMBL10638241 | 0.81 | PARP1 (0.55) | MGLLTNKS2PARP1EGLN1TNKS | |
| SCHEMBL3025892 | 0.81 | EGLN1 (0.72) | EGLN1 | |
| SCHEMBL10640188 | 0.80 | MGLL (0.48) | MGLLTNKS2PARP1HTR3AEGLN1 | |
| SCHEMBL10633927 | 0.79 | EGLN1 (0.54) | MGLLEGLN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4644000-A | FUNGICIDES, BACTERICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-17 | — | — | US | claimed |
| EP-0161418-B1 | ANTIMICROBIAL AGENTS CONTAINING 2-(1H-PYRAZOL-1-YL)-4-(3H)-QUINAZOLINONES | BAYER AG (DE) | 1988-09-07 | — | — | EP | disclosed |
| US-4644000-A | FUNGICIDES, BACTERICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-17 | — | — | US | disclosed |
| EP-0161418-A1 | Antimicrobial agents containing 2-(1H-pyrazol-1-yl)-4-(3H)-quinazolinones | BAYER AG (DE) | 1985-11-21 | — | — | EP | disclosed |