Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.44 |
| ▸ | BCHE | P06276 | 13/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167545 | 0.84 | ACHE (0.44) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10351570 | 0.83 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10638168 | 0.81 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10638105 | 0.74 | ACHE (0.67) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9163178 | 0.73 | TNKS (0.46) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9171294 | 0.73 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9168192 | 0.72 | ACHE (0.64) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9171949 | 0.71 | ACHE (0.42) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL10638199 | 0.71 | ACHE (0.59) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9171950 | 0.71 | TNKS (0.46) | ACHEBCHEGRIN1GRIN2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762841-A | Substituted 9-amino-spiro(cycloalkyl(b)quinoline-2,1'cycloalkanes) | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-08-09 | — | — | US | claimed |