Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.62 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638940 | 0.89 | LTB4R (0.50) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL8583520 | 0.86 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| SCHEMBL10635555 | 0.85 | CYSLTR1 (0.70) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10638633 | 0.84 | MAOB (0.49) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10638585 | 0.83 | CYSLTR1 (0.59) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL10636370 | 0.83 | LTB4R (0.57) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| SCHEMBL10638675 | 0.82 | LTB4R (0.64) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 | |
| SCHEMBL8586654 | 0.82 | LTB4R (0.59) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| SCHEMBL8670848 | 0.82 | LTB4R (0.61) | LTB4RLTB4R2CYSLTR1CYSLTR2 | |
| SCHEMBL9821707 | 0.81 | LTB4R (0.79) | LTB4RLTB4R2CYSLTR1CYSLTR2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788214-A | ANTIALLERGENS | HOFFMAN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4785017-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-15 | — | — | US | disclosed |