Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586654 | 0.92 | LTB4R (0.59) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL9821777 | 0.91 | LTB4R (0.62) | LTB4RLTB4R2 | |
| SCHEMBL10636370 | 0.89 | LTB4R (0.57) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8661184 | 0.89 | LTB4R (0.75) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8995684 | 0.84 | LTB4R (0.64) | LTB4RLTB4R2 | |
| SCHEMBL9048704 | 0.83 | LTB4R (0.85) | LTB4RLTB4R2 | |
| SCHEMBL8957123 | 0.82 | LTB4R (0.61) | LTB4RLTB4R2 | |
| SCHEMBL8583520 | 0.82 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10639079 | 0.82 | LTB4R (0.62) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8957027 | 0.82 | LTB4R (0.60) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579412-B1 | 1,2,4-trioxygenated benzene derivatives useful as a leukotriene antagonists | LILLY CO ELI (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5352690-A | For asthma, allergies | ELI LILLY AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0579412-A1 | 1,2,4-trioxygenated benzene derivatives useful as a leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |