Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | CASP1 | P29466 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635631 | 0.91 | KDM4E (0.54) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6947170 | 0.85 | ALDH1A1 (0.49) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL10705202 | 0.84 | AKT1 (0.67) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6954418 | 0.79 | MAOB (0.56) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL11112855 | 0.79 | AKT1 (0.69) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL10636272 | 0.78 | AKT1 (0.58) | AKT1KMT2AKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6947178 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL6952737 | 0.77 | KDM4E (0.46) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2784941 | 0.76 | AKT1 (0.72) | AKT1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2783197 | 0.76 | AKT1 (0.72) | AKT1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788214-A | ANTIALLERGENS | HOFFMAN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4785017-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-15 | — | — | US | disclosed |