Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814998 | 0.92 | MAPT (0.33) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10641056 | 0.89 | TDP1 (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10493074 | 0.89 | MAPT (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10641157 | 0.87 | MAPT (0.31) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10931241 | 0.84 | MAPT (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10996640 | 0.81 | MAPT (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10702686 | 0.81 | LMNA (0.31) | MEN1KMT2ACCKBR | |
| SCHEMBL10834483 | 0.80 | MAPT (0.36) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10493034 | 0.80 | MAPT (0.36) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10635119 | 0.79 | MEN1 (0.39) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114752-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-04-06 | — | — | EP | disclosed |
| US-4670431-A | Beta-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1987-06-02 | — | — | US | disclosed |