Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640155 | 1.00 | KDM4E (0.40) | KDM4ES1PR1S1PR3KMT2AGAA | |
| SCHEMBL10638480 | 0.80 | PPARA (0.60) | KDM4EKMT2APPARAPOLBMEN1 | |
| SCHEMBL10638439 | 0.80 | KDM4E (0.47) | KDM4EPPARAACHETDP1HDAC1 | |
| SCHEMBL10638443 | 0.80 | KDM4E (0.47) | KDM4EPPARAACHETDP1HDAC1 | |
| SCHEMBL10638488 | 0.80 | PPARA (0.60) | KDM4EKMT2APPARAPOLBMEN1 | |
| SCHEMBL10635838 | 0.79 | PPARA (0.42) | KDM4ES1PR1S1PR3KMT2AGAA | |
| SCHEMBL10635845 | 0.79 | PPARA (0.42) | KDM4ES1PR1S1PR3KMT2AGAA | |
| SCHEMBL10641719 | 0.79 | PPARA (0.41) | KDM4ES1PR1KMT2APPARAMEN1 | |
| SCHEMBL10641494 | 0.79 | PPARA (0.59) | S1PR1S1PR3PPARAFFAR1HDAC3 | |
| SCHEMBL10641499 | 0.79 | PPARA (0.59) | S1PR1S1PR3PPARAFFAR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134337-B1 | SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | claimed |