Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640332 | 0.83 | PPARA (0.52) | PPARATSHRKDM4EMAPTALOX15 | |
| SCHEMBL10641703 | 0.81 | PPARA (0.41) | PPARACYP3A4TSHRKDM4ETP53 | |
| SCHEMBL10641727 | 0.81 | PPARA (0.41) | PPARACYP3A4TSHRKDM4ETP53 | |
| SCHEMBL10640155 | 0.79 | KDM4E (0.40) | PPARAKDM4EKMT2AMEN1TDP1 | |
| SCHEMBL10640153 | 0.79 | KDM4E (0.40) | PPARAKDM4EKMT2AMEN1TDP1 | |
| SCHEMBL10641711 | 0.77 | FDPS (0.43) | PPARAKDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL10639810 | 0.77 | TSHR (0.54) | PPARATSHRKDM4EMAPTALOX15 | |
| SCHEMBL10641742 | 0.76 | NR1H4 (0.41) | PPARACYP3A4TSHRKDM4ETP53 | |
| SCHEMBL9540088 | 0.72 | PPARA (0.56) | PPARATSHRSMN1; SMN2PPARGCYP1A2 | |
| SCHEMBL10635725 | 0.70 | PPARA (0.55) | PPARATSHRKDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134337-B1 | SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | claimed |