Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.65 |
| ▸ | EGFR | P00533 | 7/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17810121 | 0.85 | EGFR (0.88) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL11432956 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL11432961 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL23255173 | 0.81 | HPGD (0.62) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL15145156 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL13486015 | 0.79 | ALDH1A1 (0.59) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL10645286 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL6213506 | 0.77 | EGFR (1.00) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL6213511 | 0.77 | EGFR (1.00) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL14703456 | 0.76 | ALDH1A1 (0.69) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4726942-A | SUNSCREEN AGENTS | L'OREAL (FR) | 1988-02-23 | — | — | US | claimed |