Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639201 | 0.89 | SLC6A4 (0.44) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10641495 | 0.89 | SLC6A3 (0.39) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10636994 | 0.87 | FPR1 (0.42) | SLC6A3SLC6A4 | |
| SCHEMBL10640723 | 0.85 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10640683 | 0.84 | SLC6A3 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10639549 | 0.83 | TP53 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10639726 | 0.83 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10637719 | 0.82 | FPR1 (0.42) | — | |
| SCHEMBL5476708 | 0.82 | NPSR1 (0.46) | — | |
| SCHEMBL10639220 | 0.79 | GPBAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164853-B1 | (SUBSTITUTED-PHENYL)-5-OXO-2-PYRROLIDINEPROPANOIC ACIDS, A PROCESS FOR PRODUCING THE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | claimed |
| US-4584313-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | claimed |
| EP-0164853-A1 | (substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | claimed |
| EP-0164852-B1 | 1-(SUBSTITUTED-ARYL)-DIHYDRO-1H-PYRROLIZINE-3,5-(2H,6H-)DIONES, A PROCESS FOR PRODUCING THE COMPOUNDS AND A PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0164853-B1 | (SUBSTITUTED-PHENYL)-5-OXO-2-PYRROLIDINEPROPANOIC ACIDS, A PROCESS FOR PRODUCING THE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4584313-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0164853-A1 | (substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| EP-0164852-A1 | 1-(Substituted-aryl)-Dihydro-1H-pyrrolizine-3,5-(2H,6H-)diones, a process for producing the compounds and a pharmaceutical composition comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4548947-A | 1-(Substituted-aryl)-dihydro-1H-pyrrolizine-3,5-[2H,6H-]diones and use for reversing amnesia | WARNER-LAMBERT COMPANY (US) | 1985-10-22 | — | — | US | disclosed |