Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | MITF | O75030 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085130 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNACYP19A1CA1 | |
| SCHEMBL5085124 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNACYP19A1CA1 | |
| SCHEMBL545429 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL13476390 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL16387737 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL6701412 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL13476726 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL14226245 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL6737565 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 | |
| SCHEMBL13674746 | 0.84 | EPHX1 (0.57) | ALDH1A1HPGDLMNACYP19A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762944-A | ANTIULCER, ANTISECRETORY AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1988-08-09 | — | — | US | disclosed |