Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 2/20 | 0.49 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147206 | 0.81 | PKM (0.71) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL28805360 | 0.80 | RAB9A (0.72) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL10893560 | 0.74 | MEN1 (0.72) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL10886823 | 0.74 | CA1 (0.72) | GAAMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL18921815 | 0.73 | GAA (0.66) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL1163865 | 0.72 | KDM4E (0.67) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL28972147 | 0.72 | RAB9A (0.52) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL30218936 | 0.72 | RAB9A (0.52) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL28972145 | 0.72 | RAB9A (0.52) | PKMRAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL18921832 | 0.72 | GAA (0.65) | PKMRAB9ASMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122321-B1 | HYDROXYBENZYLAMINO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | MERCK & CO. INC. (US) | 1988-08-03 | — | — | EP | claimed |
| US-4578390-A | SKIN DISORDERS; TOPICAL | MERCK & CO., INC. (US) | 1986-03-25 | — | — | US | claimed |
| EP-0122321-A1 | Hydroxybenzylamino derivatives as anti-inflammatory agents | MERCK & CO. INC. (US) | 1984-10-24 | — | — | EP | claimed |
| EP-0122321-B1 | HYDROXYBENZYLAMINO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | MERCK & CO. INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4578390-A | SKIN DISORDERS; TOPICAL | MERCK & CO., INC. (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0122321-A1 | Hydroxybenzylamino derivatives as anti-inflammatory agents | MERCK & CO. INC. (US) | 1984-10-24 | — | — | EP | disclosed |