Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064229 | 1.00 | MAPK1 (0.48) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL1058359 | 0.86 | KIF11 (0.49) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL6215191 | 0.83 | MAPK1 (0.46) | MAPK1KMT2AMEN1B3GNT2POLB | |
| SCHEMBL6216031 | 0.83 | B3GNT2 (0.46) | MAPK1ALDH1A1KDM4EHPGDCA12 | |
| SCHEMBL3685482 | 0.83 | ALDH1A1 (0.51) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL17242498 | 0.83 | ALDH1A1 (0.51) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL1065379 | 0.80 | HDAC1 (0.64) | MAPK1 | |
| SCHEMBL6390385 | 0.79 | MAPK1 (0.46) | MAPK1CA12CA9B3GNT2 | |
| SCHEMBL25335125 | 0.78 | ALDH1A1 (0.55) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL31160981 | 0.78 | ALDH1A1 (0.55) | MAPK1ALDH1A1L3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |