SCHEMBL1064261

SCHEMBL1064261

COC(=O)CC(O)CCCCCCOc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.49
HDAC2 Q92769 5/20 0.49
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
PPARG P37231 2/20 0.46
PPARA Q07869 1/20 0.46
HDAC3 O15379 3/20 0.46
HDAC4 P56524 3/20 0.46
HDAC7 Q8WUI4 3/20 0.46
HDAC10 Q969S8 3/20 0.46
HDAC11 Q96DB2 3/20 0.46
HDAC8 Q9BY41 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
HDAC9 Q9UKV0 3/20 0.46
HDAC5 Q9UQL6 3/20 0.46
HPGD P15428 1/20 0.46
KCNA3 P22001 1/20 0.46
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083666 1.00 HDAC1 (0.49) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL4653919 1.00 HDAC1 (0.49) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL4656181 0.99 TDP1 (0.48) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL4654986 0.94 TDP1 (0.52) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL4655066 0.90 RAB9A (0.50) TDP1L3MBTL1MAPTRAB9APPARG
SCHEMBL14593532 0.86 HPGD (0.49) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL14593496 0.86 HPGD (0.49) HDAC1HDAC2TDP1L3MBTL1MAPT
SCHEMBL1138982 0.85 KCNA3 (0.52) HDAC1HDAC2TDP1L3MBTL1HDAC3
SCHEMBL1065894 0.85 KCNA3 (0.52) HDAC1HDAC2TDP1L3MBTL1HDAC3
SCHEMBL1066086 0.85 KCNA3 (0.52) HDAC1HDAC2TDP1L3MBTL1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658403-B2 Method for producing polyhydroxyalkanoic acid INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2014-02-25 US disclosed
US-20110020886-A1 METHOD FOR PRODUCING POLYHYDROXYALKANOIC ACID INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2011-01-27 US disclosed
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed