SCHEMBL4656181

SCHEMBL4656181

COC(=O)CC(O)CCCCOc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
KCNA3 P22001 1/20 0.47
HPGD P15428 2/20 0.47
HDAC1 Q13547 4/20 0.47
HDAC2 Q92769 4/20 0.47
RECQL P46063 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MMP1 P03956 2/20 0.45
MMP3 P08254 2/20 0.45
PPARG P37231 2/20 0.44
PPARA Q07869 1/20 0.44
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC7 Q8WUI4 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083666 0.99 HDAC1 (0.49) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL1064261 0.99 HDAC1 (0.49) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL4653919 0.99 HDAC1 (0.49) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL4654986 0.95 TDP1 (0.52) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL4655066 0.91 RAB9A (0.50) TDP1L3MBTL1MAPTRAB9AHPGD
SCHEMBL14593397 0.85 HPGD (0.50) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL1067167 0.84 KCNA3 (0.53) TDP1L3MBTL1KCNA3HDAC1HDAC2
SCHEMBL14593532 0.84 HPGD (0.49) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL14593496 0.84 HPGD (0.49) TDP1L3MBTL1MAPTRAB9AKCNA3
SCHEMBL1138982 0.83 KCNA3 (0.52) TDP1L3MBTL1KCNA3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed