Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659066 | 0.97 | KDM4E (0.50) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9659244 | 0.97 | KDM4E (0.58) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9656750 | 0.89 | KDM4E (0.61) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9659163 | 0.88 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9659420 | 0.88 | KDM4E (0.47) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9656393 | 0.85 | KDM4E (0.46) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9629451 | 0.84 | KDM4E (0.54) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL10706974 | 0.83 | KDM4E (0.44) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL9654788 | 0.83 | ALDH1A1 (0.47) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL30003074 | 0.83 | HSD17B10 (0.56) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | claimed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |