SCHEMBL10643273

SCHEMBL10643273

CCCCCCCCCCCCCCCCOOC(CO)COCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.38
PLA2G10 O15496 1/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G5 P39877 1/20 0.38
USP2 O75604 1/20 0.37
TK2 O00142 5/20 0.35
KIF11 P52732 1/20 0.35
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
DUT P33316 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
CNR1 P21554 4/20 0.33
CNR2 P34972 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10646140 0.88 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10554070 0.82 USP2 (0.40) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10558219 0.82 USP2 (0.40) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10554072 0.82 USP2 (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10552104 0.82 USP2 (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10553963 0.82 USP2 (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10553120 0.82 USP2 (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10687801 0.80 USP2 (0.42) PLA2G2APLA2G10PLA2G1BPLA2G5USP2
SCHEMBL10551620 0.79 PLA2G2A (0.39) PLA2G2APLA2G10PLA2G1BPLA2G5TK2
SCHEMBL8353837 0.78 PLA2G2A (0.53) PLA2G2APLA2G10PLA2G1BPLA2G5CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254540-A2 Glycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-01-27 EP disclosed