SCHEMBL10646140

SCHEMBL10646140

CCCCCCCCCCCCCCCCCCOC(CO)COCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.45
PLA2G10 O15496 1/20 0.45
PLA2G1B P04054 1/20 0.45
PLA2G5 P39877 1/20 0.45
CNR2 P34972 8/20 0.41
CNR1 P21554 6/20 0.41
ALDH1A1 P00352 1/20 0.40
LPAR1 Q92633 4/20 0.39
LPAR3 Q9UBY5 4/20 0.39
LPAR2 Q9HBW0 1/20 0.39
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8353837 0.90 PLA2G2A (0.53) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL8356181 0.90 PLA2G2A (0.53) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL8195323 0.90 PLA2G2A (0.53) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL8350184 0.90 PLA2G2A (0.53) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL10643273 0.88 PLA2G2A (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL10687801 0.86 USP2 (0.42) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL24207772 0.85 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL24208022 0.85 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL24207927 0.85 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2
SCHEMBL24208011 0.85 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254540-A2 Glycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-01-27 EP disclosed