Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.39 |
| ▸ | RARG | P13631 | 13/20 | 0.39 |
| ▸ | RARA | P10276 | 10/20 | 0.39 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648465 | 0.87 | RARB (0.39) | RARBRARGRARARXRARXRB | |
| SCHEMBL10645859 | 0.85 | RARB (0.42) | RARBRARGRARARXRARXRB | |
| SCHEMBL10643410 | 0.78 | RXRA (0.55) | RARBRARGRARARXRARXRB | |
| 4-Aminophenol SCHEMBL10851272 | 0.69 | RARB (0.62) | RARBRARGRARARXRARXRB | |
| 4-Aminophenol SCHEMBL10851260 | 0.69 | RARB (0.62) | RARBRARGRARARXRARXRB | |
| SCHEMBL10775733 | 0.69 | RARB (0.46) | RARBRARGRARARXRARXRB | |
| SCHEMBL10648467 | 0.66 | RXRA (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL10842818 | 0.66 | RARB (0.74) | RARBRARGRARARXRARXRB | |
| SCHEMBL10844307 | 0.66 | RARB (0.74) | RARBRARGRARARXRARXRB | |
| SCHEMBL10733163 | 0.66 | RXRA (0.55) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232779-B1 | VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| EP-0232779-A1 | Vinyl phenol derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | disclosed |