Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.39 |
| ▸ | RARG | P13631 | 10/20 | 0.39 |
| ▸ | RARA | P10276 | 8/20 | 0.39 |
| ▸ | RXRA | P19793 | 7/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645859 | 0.89 | RARB (0.42) | RARBRARGRARARXRARXRB | |
| SCHEMBL10643402 | 0.87 | RARB (0.39) | RARBRARGRARARXRARXRB | |
| SCHEMBL10648467 | 0.80 | RXRA (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL10733163 | 0.80 | RXRA (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL10729621 | 0.75 | RARB (0.48) | RARBRARGRARARXRARXRB | |
| SCHEMBL10729613 | 0.75 | RARB (0.48) | RARBRARGRARARXRARXRB | |
| SCHEMBL10643383 | 0.74 | TUBB1 (0.38) | RARBRARGRARARXRARXRB | |
| SCHEMBL10773042 | 0.71 | RARB (0.46) | RARBRARGRARARXRARXRB | |
| SCHEMBL10646843 | 0.69 | NQO2 (0.46) | TUBB1NQO2PTGS1PTGS2KDM4E | |
| SCHEMBL10643949 | 0.69 | RXRA (0.72) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232779-B1 | VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| EP-0232779-A1 | Vinyl phenol derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | disclosed |