Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.50 |
| ▸ | CDK2 | P24941 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642386 | 0.89 | CCNE1 (0.51) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL13951638 | 0.86 | CCNE1 (0.48) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL9123481 | 0.83 | BLM (0.62) | CCNE1CDK2CDK1CCNB1BLM | |
| Ammonia Solution, Strong SCHEMBL10907047 | 0.82 | BLM (0.60) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL13625720 | 0.81 | BLM (0.45) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL14393416 | 0.81 | BLM (0.45) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL10404957 | 0.78 | CCNE1 (0.52) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL10904901 | 0.77 | CCNE1 (0.56) | CCNE1CDK2CDK1CCNB1BLM | |
| SCHEMBL10640340 | 0.77 | BLM (0.39) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL24829634 | 0.77 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072027-B1 | ANTIVIRAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-05-18 | — | — | EP | disclosed |