Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CDK1 | P06493 | 4/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.47 |
| ▸ | AHCY | P23526 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964251 | 0.85 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL22448462 | 0.84 | AHCY (0.67) | AHCYADORA2AADORA1ALDH1A1 | |
| SCHEMBL20671021 | 0.84 | AHCY (0.67) | AHCYADORA2AADORA1ALDH1A1 | |
| SCHEMBL23710566 | 0.81 | AHCY (0.68) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL10642386 | 0.80 | CCNE1 (0.51) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL7263234 | 0.80 | ADORA2A (0.67) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL7268668 | 0.80 | ADORA2A (0.67) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL7263232 | 0.80 | ADORA2A (0.67) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL7749494 | 0.80 | CCNE1 (0.65) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL16131314 | 0.80 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MERCK SHARP & DOHME LLC (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MAVS, TLR3, DDX18 | CCNE1 4435/4885CDK2 3569/4885CDK1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.